An exhausted, workaholic actress, Anna Baskin, 44, abruptly extricates herself from a successful but mind-numbing TV role, returning to her past life in New York to reinvent herself. But despite the desire for transformation, she cannot find herself outside of her career. When an upsetting personal betrayal unexpectedly leads to the role of her life, she must confront the reality of her past relationships in order to clear a path forward. The intimate story of Anna and her friends Isaac and Kate become magnified by the film's surrounding themes: gentrification, addiction, autoimmune disease, burnout, sexism in the film industry and 21st century marketing of the self.

Jack and Diane, two teenage girls, meet in New York City and spend the night kissing ferociously. Diane's charming innocence quickly begins to open Jack's tough skinned heart. But, when Jack discovers that Diane is leaving the country in a week she tries to push her away. Diane must struggle to keep their love alive while hiding the secret that her newly awakened sexual desire is giving her werewolf-like visions.

Teenagers Rose and Bennett were in love, and then a car crash claimed Bennett's life. He left behind a grieving mother, father and younger brother, and Rose was left all alone. She has no family to turn to for support, so when she finds out she's pregnant, she winds up at the Brewer's door. She needs their help, and although they can't quite admit it, they each need her so they can begin to heal.

In the early 1960's, sixteen year old Jenny Mellor lives with her parents in the London suburb of Twickenham. On her father's wishes, everything that Jenny does is in the sole pursuit of being accepted into Oxford, as he wants her to have a better life than he. Jenny is bright, pretty, hard working but also naturally gifted. The only problems her father may perceive in her life is her issue with learning Latin, and her dating a boy named Graham, who is nice but socially awkward. Jenny's life changes after she meets David Goldman, a man over twice her age. David goes out of his way to show Jenny and her family that his interest in her is not improper and that he wants solely to expose her to cultural activities which she enjoys. Jenny quickly gets accustomed to the life to which David and his constant companions, Danny and Helen, have shown her, and Jenny and David's relationship does move into becoming a romantic one...

Tale of a father who struggles to bond with his estranged son Gabriel, after Gabriel suffers from a brain tumor that prevents him from forming new memories. With Gabriel unable to shed the beliefs and interests that caused their physical and emotional distance, Henry must learn to embrace his son's choices and try to connect with him through music.

Frequently cynical screenwriter Charlie Kaufman has just taken on a new assignment. That is, to adapt writer Susan Orlean's "The Orchid Thief" into a screenplay, all of it based on the life of the eccentric John Laroche, an exotic plant collector based out of Florida. While his easygoing twin brother Donald, is writing scripts with ease, Charlie finds himself on a perpetual struggle that never seems to end.

The story of Bettie Page, uber-successful 1950's pin-up model, one of the first sex icons in America, and the target of a Senate investigation (based on her bondage photos).

Anna is a young widow who is finally getting on with her life after the death of her husband, Sean. Now engaged to be married, Anna meets a ten-year-old boy who tells her he is Sean reincarnated. Though his story is both unsettling and absurd, Anna can't get the boy out of her mind. And much to the concern of her fiancé, her increased contact with him leads her to question the choices she has made in her life.